An investigational topical gel for reversible male contraception.


Apply once a day
On the shoulders and upper arms – morning or night. Designed to deliver a consistent amount and dry fast to easily fit into anyone's routine.
Novel combination of two hormones
NES/T is an investigational combination of two hormones that are individually approved by the FDA for other uses. Designed to temporarily pause sperm production while maintaining normal testosterone levels.
Reliable and reversible
Clinical trials have shown that most men reach contraceptive levels within a couple months of use. Upon stopping use of NES/T, sperm levels rise and fertility is restored.
"I've only experienced increased libido. Maybe I'm just lucking out but I hope this is the case for the majority of participants. If it is, it's definitely going to change contraception as a whole."

Matthew Treviño & Emily Fletcher
Phase 2b Trial Participants
Select research on NES/T and hormonal male contraception.